镉对雄性动物生殖功能影响的研究进展

雄性生殖系统对镉较为敏感，镉可损伤雄性动物的精巢组织，包括睾丸中的各级生精细胞、类固醇分泌细胞、类固醇激素和酶水平等，从而降低精子质量、受精率和繁殖率，导致雄性动物生殖功能受到影响。镉对雄性性腺的毒性效应是镉与动物体相互作用的结果，在综述镉对雄性生殖系统影响的同时，进一步分析了镉可能对雄性性腺产生的毒性机制，以及镉在导致雄性性腺产生毒性效应的同时，所引起动物机体迅速启动一类应激蛋白即金属硫蛋白（metallothionein，MT）的应答反应，以保护机体免受镉的损伤。

Advance in Toxic Effects of Cadmium in Male Animal Reproduction Function

Male animal genital system is susceptibility to cadmium.Cadmium could destroy testis including spermatogenic cell,steroid-secreting cell,the steroid hormone and levels,and enzyme,reducing sperm quality,fertilization rate and reproduction rate,and male animal reproduction function is affected.Toxic effect of cadmium on male animal genital system is the result of interaction of cadmium and animal.Metallothionein(MT) could be induced by cadmium,suggested to play a role in the homeostasis of cadmium,in the detoxification of cadmium.