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| 外源褪黑激素对昆明白鼠生长和繁殖性能的影响 | |
| 引用本文： | 史建民,李红玲,史文清,张洪海,刘国世. 外源褪黑激素对昆明白鼠生长和繁殖性能的影响[J]. 中国畜牧杂志, 2008, 44(21) |
| 作者姓名： | 史建民 李红玲 史文清 张洪海 刘国世 |
| 作者单位： | 1. 中国农业大学动物科技学院,北京,100193 2. 北京市畜牧兽医总站,北京,100107 3. 曲阜师范大学生物系,山东,曲阜,273165 4. 中国农业大学动物科技学院,北京,100193;农业生物技术国家重点实验室,北京,100193 |
| 基金项目： | 山东省科技攻关项目，山东省教育厅资助项目，北京市科委科研项目，北京市农委资助项目 |
| 摘 要： | 研究外源褪黑激素(MT)对昆明白小鼠生长和繁殖性能的影响,为外源MT在畜牧生产上的应用提供依据。将40只昆明白小鼠(公、母各半)随机分成4组,用皮下埋植的方法埋植不同剂量(0、1、4、8mg)的外源MT,每3d称量1次小鼠的体重并记录;MT处理11周后,试验公鼠与正常母鼠交配,记录受精卵的数量;试验母鼠与正常公鼠交配,记录冲出卵的数量,14周后HE染色,制作睾丸和卵巢切片。在体重增长方面,外源MT对昆明白公鼠体重增长有促进作用,皮下埋植8mg组的促进作用显著(P<0.05);对昆明白母鼠体重增长有抑制作用,皮下埋植8mg组的抑制作用显著(P<0.05)。在繁殖性能方面,外源MT对昆明白鼠公鼠繁殖性能抑制作用显著,皮下埋植1mg和4mg组抑制作用显著(P<0.05),但皮下埋植外源MT8mg组和对照组间无统计学差异(P>0.05)。外源MT对昆明白鼠生长和繁殖性能有影响,并存在性别和剂量的依赖性。 |
| 关 键 词： | 褪黑激素 生长 睾丸 卵巢 小鼠 |
Effect of Melatonin on the Growth and Reproduction Performance in Kunming Mice |
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| SHI Jian-min,LI Hong-ling,SHI Wen-qing,ZHANG Hong-hai,LIU Guo-shi. Effect of Melatonin on the Growth and Reproduction Performance in Kunming Mice[J]. Chinese Journal of Animal Science, 2008, 44(21) | |
| Authors: | SHI Jian-min LI Hong-ling SHI Wen-qing ZHANG Hong-hai LIU Guo-shi |
| Abstract: | The effects of melatonin on the growth and reproduction of Kunming mice were investigated.According sex and weight, a total of 40 Kunming mice were divided into four groups, with each group 10 mice(male:female=1:1) and were implanted with a special dose of melatonin.The implantation of 8 mg melatonin promoted the growth of male mice(P < 0.05) and restrained the growth of female mice(P < 0.05).The implantation of 1mg and 4mg melatonin had effect on the reproduction, while the effect was only significant on male mice(P < 0.05).The implantation of melatonin had effect on the growth and reproduction of Kunming mice, and the effect was dependent on sex and dose. |
| Keywords: | melatonin growth testis ovary mice |
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