| 多粘菌素B导致脂质体相变的分离及其抗菌机理的探讨 |
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| 引用本文： | 王海婴 Bogg.,JM.多粘菌素B导致脂质体相变的分离及其抗菌机理的探讨[J].华中农业大学学报,1989,8(2):163-167. |
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| 作者姓名： | 王海婴 Bogg. JM |
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| 作者单位： | 华中农业大学，The hospital for sick children，Toronto，Canada |
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| 摘 要： |
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| 关 键 词： | 多粘菌素B 抗菌机理 交错对插 相变 |
POLYMYXIN B INDUCED PHASE SEPARATION OF LIPID AND EXPLORATION OF THE MECHANISM FOR BACTERIA RESISTANCE |
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| Wang Haiying.POLYMYXIN B INDUCED PHASE SEPARATION OF LIPID AND EXPLORATION OF THE MECHANISM FOR BACTERIA RESISTANCE[J].Journal of Huazhong Agricultural University,1989,8(2):163-167. |
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| Authors: | Wang Haiying |
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| Abstract: | Differential scanning calorimetry ( D. S. C. ) and electron spin resonance (E. S. R. ) experiments were carried out to examine the effect of the polymyxin B ( PL B ) on the phase separation and Change order of the fatty acid chains of dipalmitoylpho sphatidic acid ( DPPA ) , dipalmitoylphosphatidylglycerol ( DPPG ) and dipalmitoylpho sphatidylcholine (DPPC). It is shown that in both DPPA and DPPG alone or DPPA/DPPC and DPPG/DPPC mix lures, PL B can induce phase separation and interdigitation bilayer in the gel state. But PL B can not induce changes in pure Dppc. |
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| Keywords: | polymyxin B mechanism of bacteria resistance phase separation interdigitation |
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