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脑灵素胶囊对小鼠中枢神经系统的影响
引用本文:翟丽杰,王奭骥,于晓风,曲绍春,徐华丽,唯大员.脑灵素胶囊对小鼠中枢神经系统的影响[J].人参研究,2007,19(1):5-7.
作者姓名:翟丽杰  王奭骥  于晓风  曲绍春  徐华丽  唯大员
作者单位:1. 吉林大学第二医院·长春·130041
2. 吉林大学药学院药理教研室·长春·130021
摘    要:通过小鼠自主活动、戊巴比妥钠阈剂量及阈下剂量催眠作用及电刺激强直性惊厥反应,观察脑灵素胶囊对中枢神经系统的影响。结果表明,脑灵素胶囊能明显减少小鼠自主活动次数,可协同戊巴比妥钠阈下剂量的催眠作用,缩短戊阈剂量巴比妥钠小鼠的入睡时间,并延长睡眠持续时间,但对小鼠电刺激强直性惊厥无明显影响。

关 键 词:脑灵素胶囊  小鼠  自主活动  戊巴比妥钠

Effects of Naolingsu Capsule on Central Nervous System in Mice
Authors:Zhai Li-jiel  Wang Shi-ji  Yu Xiao- feng  QU Shao-chun  Xu Hua-li  Sui Da-yuan
Institution:The Second Hospital of JILIN Univercity ,ChangChun , 130041;Department of harmacology, Pharmacy College JILIN Univercity, ChangChun, 130021
Abstract:The research observed the effect of Naolingsu Capsule on the central nervous system with independent activity,hypnosis of pentobarbital sodium of threshold dose and subthreshold dose,and reaction of tonic convulsion under electric stimulation in mice.The results showed that Naolingsu Capsule(2 and 4 g/kg ig for 3 days) can obviously let up the independent activity of mice,coordinate with hypnosis of pentobarbital sodium of threshold dose and subthreshold dose,shorten the time of falling asleep and extend the time of sleep time.But has no significant effect on reaction of tonic convulsion under electric stimulation in mice.
Keywords:Naolingsu Capsule  mice  independent activity  pentobarbital
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