Identification of sialyl oligosaccharides including an oligosaccharide nucleotide in colostrum of an addax (Addax nasomaculatus) (Subfamily Antelopinae) |
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| Authors: | Khuukhenbaatar Ganzorig Takuya Asakawa Masashi Sasaki Tadao Saito Isao Suzuki Kenji Fukuda Tadasu Urashima |
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| Institution: | 1. Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture & Veterinary Medicine, Obihiro, Hokkaido, Japan;2. Himeji Central Park, Toyotomicho Konandai, Himeji, Hyogo, Japan;3. Graduate School of Agriculture, Tohoku University, Sendai, Miyagi, Japan |
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| Abstract: | Mammalian milk/colostrum usually contains milk oligosaccharides along with the predominant lactose. Although milk oligosaccharides of a variety of Bovidae species including cow, sheep and goat have been characterized, those of the addax, an Antelopinae species of the Bovidae, have not as yet been clarified. In this study, several sialyl oligosaccharides were purified from a sample of addax colostrum and characterized as follows: Neu5Ac(α2‐8)Neu5Ac(α2‐3)Gal(β1‐4)Glc, Neu5Gc(α2‐8)Neu5Gc(α2‐3)Gal(β1‐4)Glc, Neu5Ac(α2‐3)Gal(β1‐4)Glc, Neu5Ac(α2‐6)Gal(β1‐4)GlcNAc, Neu5Gc(α2‐3)Gal(β1‐4)Glc, Neu5Gc(α2‐6)Gal(β1‐4)Glc, Neu5Gc(α2‐6)Gal(β1‐4)GlcNAc. In addition, an oligosaccharide nucleotide Neu5Gc(α2‐6)Gal(β1‐4)GlcNAcα1‐UDP was characterized. Molecular species of a variety of sialyl oligosaccharides found in milk and colostrum of these Bovidae were compared. |
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| Keywords: | addax colostrum Bovidae milk oligosaccharides milk sugar nucleotide sialyl milk oligosaccharides |
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