首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Ectopic Tissue Consisting of a Mixture of Glandular Gastric,Intestinal, and Exocrine Pancreatic Tissue in the Forestomach of a Rat
Authors:Yuki Kato  Akihiro Hirata  Emi Kashiwagi-Yamamoto  Koichi Masuno  Kae Fujisawa  Shuuichi Matsushima  Nobuo Takasu
Institution:1) Developmental Research Laboratories, Shionogi & Co., Ltd., 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan;2) Division of Animal Experiment, Life Science Research Center, Gifu University, 1–1 Yanagido, Gifu 501–1194, Japan;3) Laboratory of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University, Rinkuu Ourai Kita 1-58, Izumisano, Osaka 598-8531, Japan
Abstract:The development of ectopic gastric, intestinal, or pancreatic tissue in the gastrointestinal tract is extremely rare in rats, although it is fairly common in humans. In this report, we describe an unusual case in which a mixture of different types of ectopic tissue was found in the forestomach of a rat. A solitary white nodular/polypoid structure, which measured 5 mm in size, was detected on the luminal surface of the greater curvature of the forestomach in an 8-week-old female Crl:CD(SD) rat. A histological examination revealed that the lesion contained ectopic glandular gastric tissue, including gastric surface mucous cells, parietal cells, and pyloric gland cells, which was confirmed by immunohistochemistry. Moreover, the lesion also contained villin-positive columnar intestinal absorptive cells and chymotrypsin-positive pancreatic exocrine tissue. To the best of our knowledge, this is the first study to detect a mixture of ectopic glandular gastric, intestinal, and exocrine pancreatic tissue in a rat.
Keywords:choristoma  ectopic  forestomach  heterotopic  rat
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号