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Spontaneous complex odontoma in a Sprague-Dawley rat
Authors:Jang Dong Deuk  Kim Chuel-Kyu  Ahn Byeongwoo  Kang Jin Seok  Nam Ki Tack  Kim Dae Joong  Han Dong Un  Jung Kwonil  Chung Han-Kook  Ha Seung-Kwon  Choi Changsun  Cho Wan-Seob  Kim Junghyun  Chae Chanhee
Affiliation:Korea Food and Drug Administration, Department of Pathology, Seoul.
Abstract:Complex odontoma from a female Sprague-Dawley rat is described histopathologically. Necropsy revealed a hard (bony), white mass (3.0 x 3.0 x 2.1 cm) on the left mandible. Microscopically, the mass consisted of islands or nests of epithelial and mesenchymal elements that formed abortive tooth structures. In other areas, tooth formation consisted of a pulp cavity lined by layers of odontoblasts, dentin, enamel, and ameloblasts. Concerning all features of normal tooth formation which was differentiated and mineralized yet completely disorganized, the diagnosis of complex odontoma was recommended.
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