| 紫斑谷螟豹皮樟虫茶小鼠急性毒性和骨髓红细胞微核试验研究 |
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| 引用本文： | 王芳,陈松,刘仁普,杨茂发.紫斑谷螟豹皮樟虫茶小鼠急性毒性和骨髓红细胞微核试验研究[J].贵州大学学报(农业与生物科学版),2017,36(5). |
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| 作者姓名： | 王芳 陈松 刘仁普 杨茂发 |
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| 作者单位： | 贵州大学昆虫研究所/贵州山地农业病虫害重点试验室,贵州贵阳,550025 |
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| 基金项目： | 国家自然科学基金项目“贵州主要虫茶昆虫生物学生态学及所产虫茶评价研究” |
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| 摘 要： | 用小鼠最大耐受量法、小鼠骨髓嗜多染红细胞微核试验和小鼠精子畸形试验等方法,究紫斑谷螟豹皮樟虫茶对小鼠的急性毒性和致突变性作用。结果显示,紫斑谷螟豹皮樟虫茶的小鼠急性经口LD5030 g/kg·bw,小鼠骨髓红细胞微核试验结果为阴性。结果表明,紫斑谷螟豹皮樟虫茶属无毒物,对小鼠体细胞无致突变性。
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| 关 键 词： | 急性毒性 微核试验 致突变作用 小鼠 |
Acute Toxicity Test and Micronucleus Test of Pyralis Farinalis-Litsea Coreana Insect Tea in Mice |
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| WANG Fang,CHEN Song,LIU Ren-pu,YANG Mao-fa.Acute Toxicity Test and Micronucleus Test of Pyralis Farinalis-Litsea Coreana Insect Tea in Mice[J].Journal of Mountain Agriculture & Biology,2017,36(5). |
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| Authors: | WANG Fang CHEN Song LIU Ren-pu YANG Mao-fa |
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| Abstract: | The acute toxicity and mutagenicity of Pyralisfarinalis-Litsea coreana Insect Tea in mice were investigated.Acute toxicity test,bone marrow polychromatic erythrocyte micronucleus test in mice were adopted.The results showed that the acute oral maximum LD5owas higher than 30 g/kg · bw;the micronucleus test indicated that the difference between treating group and negative control group was not remarkable.The results proved that the Pyralis farinalis-Litsea coreana Insect Tea is belongs to practical actox-ic and could not cause mutagenesis. |
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| Keywords: | acute toxicity test bone-marrow micronucleus test mutation mice |
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