| 西加毒素检测分析研究新进展 |
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| 引用本文： | 周秀锦,李孝军,何明,周向阳,邵宏宏,颜建波.西加毒素检测分析研究新进展[J].安徽农业科学,2013(2):800-801,810. |
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| 作者姓名： | 周秀锦 李孝军 何明 周向阳 邵宏宏 颜建波 |
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| 作者单位： | 舟山出入境检验检疫局,浙江舟山,316000 |
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| 基金项目： | 浙江省舟山市科技计划项目(10204-2) |
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| 摘 要： | 西加毒素是一种属于获得性毒素的珊瑚鱼毒素,为脂溶性多聚醚类化合物,有强烈的和不可逆的胆碱酶抑制毒性。从发现西加毒素至今,有不同的检测方法提出,但都不能满足适应市场的需求。主要对西加毒素现有的检测分析方法进行了综述,将有助于多种检测方法更好地提高与完善,对于西加毒素中毒防治、水产业的顺利发展以及公众的健康都具有重要意义。
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| 关 键 词： | 西加毒素 检测 小鼠生物法 细胞毒性检测 高效液相色谱-质谱分析 免疫学测定法 |
Research Advance on Detection and Analysis of Ciguatoxin |
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| Institution: | ZHOU Xiu-jin et al(Zhoushan Entry-exit Inspection and Quarantine Bureau,Zhoushan,Zhejiang 316000) |
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| Abstract: | Ciguatoxins（CTXs） may be an acquired coral fish toxin.CTXs are a family of lipidsoluble cyclic polyethers which have strong and irreversible choline esterase inhibition.Several approaches were developed in the past decades to address this issue because of some drawbacks are not the convenient and accurate detection method for CTXs.To provide references for detection and prevention of ciguatera fish poisoning,development of aquatic products industry,protection public health,the current detection methods of CTXs were reviewed. |
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| Keywords: | Ciguatoxin Detection Mouse bioassay Cytotoxicity assay HPLC/MS/MS Immunoassays |
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