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The Complete Genomic Sepuence of a Foot-and-Mouth Disease Virus Isolated from the Swine
Authors:LIU Guang-qing  LIU Zai-xin  ZHANG Xian-sheng  CHANG Hui-yun  GUO Hui-chen  LI Dong  LIU Xiang-tao  XIE Qing-ge
Abstract:The complete genomic sequence of foot-and-mouth disease virus (FMDV) Chinese strain OH/CHA/99 was determined. The 8 040 nt sequence and the deduced amino acid sequence were compared with FMDV sequences published. The results showed that OH/CHA/99 shared higher sequence homology with OTYTW/97, indicating their close genetic relationship. However,the strain had lower sequence identity with O1/Kaufbeuren/66 strain. Besides, large deletions in 3A coding region were observed in OH/CHA/99. It was shown that the poly (A)tail of OH/CHA/99 had 56 As at least.
Keywords:Foot-and-mouth disease virus  OH/CHA/99  3A coding region
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