A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum |
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| Authors: | Yue Kong Jun-Jun Xiao Shu-Cong Meng Xiao-Min Dong Yue-Wei Ge Ru-Feng Wang Ming-Ying Shang Shao-Qing Cai |
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| Institution: | 1. Cardiology Unit, Emergency Dept, Hospital “Madonna del Soccorso”, San Benedetto del Tronto, Italy;2. Cardiac Intensive Care, Piemonte-Papardo Hospital, Messina, Italy |
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| Abstract: | Constituents of the fruit of Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus) were investigated. A new flavonoid, 8,2′-diprenylquercetin 3-methyl ether along with 9 known compounds were isolated and identified. Among them, the new compound 8,2′-diprenylquercetin 3-methyl ether exhibited cytotoxic activities against MDA-231 and T47D breast cancer cell lines, quercetin, kaempferol and rutin were isolated from Sinopodophylli Fructus for the first time. |
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