| 诺氟沙星在菲律宾蛤仔、海湾扇贝体内的残留和消除规律研究 |
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| 引用本文： | 孔祥科,李健,常志强,韩毅颖.诺氟沙星在菲律宾蛤仔、海湾扇贝体内的残留和消除规律研究[J].河北渔业,2011(1):20-24. |
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| 作者姓名： | 孔祥科 李健 常志强 韩毅颖 |
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| 作者单位： | 1. 大连海洋大学生命科学与技术学院,辽宁,大连,116023;中国水产科学研究院黄海水产研究所,山东,青岛,266071
2. 中国水产科学研究院黄海水产研究所,山东,青岛,266071 |
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| 基金项目： | 国家虾业技术体系，公艺性农业行业专项，养殖虾类病毒病快速诊断与生物防控技术的研究及示范 |
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| 摘 要： | 首次报道了诺氟沙星在菲律宾蛤仔和海湾扇贝体内的残留和消除规律.在水温为(20 ±1) ℃的条件下,菲律宾蛤仔和海湾扇贝的混养系统中,以50 mg/L剂量连续10 d投喂诺氟沙星,取鳃、内脏团、闭壳肌等组织,进行反相高效液相色谱法测定其浓度.结果表明:诺氟沙星在3种组织中消除速率快慢不一,鳃为诺氟沙星残留的靶组织.其在菲...
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| 关 键 词： | 菲律宾蛤仔 海湾扇贝 诺氟沙星 消除 |
Residues and depletion of norfloxacin in manilaclam ruditapes philippinarum and bay scallop Argopectens irradias |
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| Institution: | KONG Xiang-ke,LI Jian,CHANG Zhi-qing(1.Dalian Ocean university,Dalian,116023,China;2.Yellow Sea Fisheres Research Institue,Qingdao 26671,China) |
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| Abstract: | The residues and depletion of norfloxacin in Ruditapes philippinarum and Argopectens irradias were first studied.Adductor muscle,gill and visceral mass were sample after feeding at dose of 50 mg/L for ten consecuitive days and twice a day.Norfloxacin analyses were performed by RP-HPLC.The results showed that the eli mination rate was deeply different in three tissues and the gill were main reservoirs of norfloxacin in Ruditapes philippinarum and Argopectens irradias.The equations of eli mination curve of norfloxacin in gill,visceral mass and adductor muscle were C = 3.985 3e-0.0241t,C = 3.475 9 e-0.0269t,C =3.646 1 e-0.0293tt in Ruditapes philippinarum,and C = 2.239 3 e-0.045t、C = 1.721 7 e-0.0484t 、C = 1.441 5 e-0.0493t in Argopectens irradias,respectively.The eli mination of half-lives（T1/2） was 28.75、25.76、23.65 h in Ruditapes philippinarum and 15.4、14.31、14.06 h in Argopectens irradias,respectively.Withdrawl times was 5d and 3d in the light of maximum residue limit of 50 μg/kg. |
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| Keywords: | Ruditapes philippinarum Argopectens irradias norfloxacin eli mination |
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