| Antifungal Flavonoids from Ficus sarmentosa var. henryi （King） Corner |
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| 引用本文： | WANG Xue-gui,WEI Xiao-yi,TIAN Yong-qing,SHEN Li-tao,XU Han-hong. Antifungal Flavonoids from Ficus sarmentosa var. henryi （King） Corner[J]. 中国农业科学(英文版), 2010, 9(5): 690-694. DOI: 10.1016/S1671-2927(09)60144-9 |
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| 作者姓名： | WANG Xue-gui WEI Xiao-yi TIAN Yong-qing SHEN Li-tao XU Han-hong |
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| 作者单位： | [1]Key Laboratory of Natural Pesticide and Chemical Biology, Ministry of Education/South China Agricultural University, Guangzhou 510642, P.R.China [2]Agricultural College, Sichuan Agricultural University, Ya＇an 625014, P.R.China [3]South China Institute of Botany, Chinese Academy of Sciences, Guangzhou 510650, P.R.China |
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| 基金项目： | The authors gratefully acknowledge the financial support by the National Nature Science Foundation of China （30571235）. |
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| 摘 要： | The methanol extract of Ficus sarmentosa var. henryi （King） Corner was found to detect potent inhibitory activities against 6 crop pathogenic fungi, Fusarium graminearum, Pumpkin fusarium Wilt, Curvularia lunata （Wakker） Boed, Septoria zeicola Stout, Botrytis cinerea, and Rhizoctonia solani. Four flavonoids were isolated from the extract of F. sarmentosa var. henryi by activity-guided fractionation and they were identified as eriodictyol （1）, homoeriodictyol （2）, dihydroquercetin （3）, and luteolin （4） by spectroscopic means and displayed excellent inhibitory activity against F. graminearum and S. zeicola. Among them, luteolin （4） showed the strongest inhibitory activity with IC50 values of 56.38 and 81.48 mg L^-1, to the fungi, respectively. The in vitro inhibitory activity of F. sarmentosa var. henryi （King） Corner was reported for the first time and the inhibitory action mechanism of luteolin （4） was worthy of further research.
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| 关 键 词： | 黄酮类化合物 珍珠莲 无花果 抗真菌 变种 锥栗 小麦赤霉病菌 甲醇提取物 |
| 收稿时间： | 2009-08-01 |
Antifungal Flavonoids from Ficus sarmentosa var. henryi (King) Corner |
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| WANG Xue-gui,WEI Xiao-yi,TIAN Yong-qing,SHEN Li-tao,XU Han-hong. Antifungal Flavonoids from Ficus sarmentosa var. henryi (King) Corner[J]. 《Agricultural Sciences in China》, 2010, 9(5): 690-694. DOI: 10.1016/S1671-2927(09)60144-9 |
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| Authors: | WANG Xue-gui WEI Xiao-yi TIAN Yong-qing SHEN Li-tao XU Han-hong |
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| Affiliation: | 1. Department of Pharmacognosy, Faculty of Pharmacy, Ataturk University, Erzurum, Turkey;2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Turkey;3. Department of Plant Biology, Institute of Biology, Kiev National University of Taras Shevchenko, Volodymyrska, 64, Kyiv, Ukraine;4. Department of Plant Physiology, Slovak University of Agriculture, Nitra, Slovak Republic;5. Department of Biology, Faculty of Science, Gazi University, Ankara, Turkey;6. Department of Pharmaceutical Botany, Faculty of Pharmacy, Ankara University, Ankara, Turkey |
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| Abstract: | The methanol extract of Ficus sarmentosa var. henryi (King) Corner was found to detect potent inhibitory activities against 6 crop pathogenic fungi, Fusarium graminearum, Pumpkin fusarium Wilt, Curvularia lunata (Wakker) Boed, Septoria zeicola Stout, Botrytis cinerea, and Rhizoctonia solani. Four flavonoids were isolated from the extract of F. sarmentosa var. henryi by activity-guided fractionation and they were identified as eriodictyol (1),homoeriodictyol (2), dihydroquercetin (3), and luteolin (4) by spectroscopic means and displayed excellent inhibitory activity against F. graminearum and S. zeicola. Among them, luteolin (4) showed the strongest inhibitory activity with IC50 values of 56.38 and 81.48 mg L-1, to the fungi, respectively. The in vitro inhibitory activity of F. sarmentosa var. henryi (King) Corner was reported for the first time and the inhibitory action mechanism of luteolin (4) was worthy of further research. |
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| Keywords: | Ficus sarmentosa var. henryi (King) Corner inhibitory activity flavonoids luteolin |
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