Biological activity of serotonin conjugates from the seeds of Centaurea nigra |
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| Authors: | Kumarasamy Y Middleton M Reid R G Nahar L Sarker S D |
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| Institution: | Phytopharmaceutical Research Laboratory, School of Pharmacy, The Robert Gordon University, Schoolhill, Aberdeen, AB10 1FR, Scotland, UK. |
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| Abstract: | Two serotonin conjugates, N-(trans-p-coumaroyl)-serotonin (1) and N-(trans-feruloyl)-serotonin (maoschamine, 2), isolated from the methanol extract of the seeds of Centaurea nigra, have been assessed for antibacterial and free radical scavenging activities. The general toxicity of 1 and 2 has also been determined by the brine shrimp lethality bioassay. |
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