Changes induced by phorate in the carbohydrate metabolism of the snail Lymnaea acuminata

Carbohydrate metabolism was studied in the hepatopancreas, mantle, intestine and foot of the snail Lymnaea acuminata, exposed to 40% and 80% of the LC₅₀ dose of phorate (12 and 24 mg litre^?1, respectively) for 24 and 48 h. Following treatment with the pesticide, the rate of oxygen consumption and the glycogen contents were reduced, while the levels of lactic acid and reducing sugars were enhanced. Withdrawal of the pesticide for 7 days after exposure of the snails to 12 mg of phorate litre^?1 for 48 h did not reverse these changes.