| 玉米赤霉烯酮和脱氧血腐镰刀菌烯醇对雌性动物的生殖毒性及作用机制 |
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| 引用本文： | 高爽,梁珍,邓俊良,杨颜铱,陈芸.玉米赤霉烯酮和脱氧血腐镰刀菌烯醇对雌性动物的生殖毒性及作用机制[J].动物营养学报,2016(4):1042-1049. |
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| 作者姓名： | 高爽 梁珍 邓俊良 杨颜铱 陈芸 |
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| 作者单位： | 四川农业大学动物医学院，动物疫病与人类健康重点实验室，环境公害与动物疾病四川省高校重点实验室，成都 611130 |
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| 基金项目： | 国家自然科学基金(31072182)，“长江学者和创新团队发展计划”创新团队项目(IRT0848)，四川农业大学双支计划(3571537) |
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| 摘 要： | 镰刀菌毒素玉米赤霉烯酮(ZEA)和脱氧血腐镰刀菌烯醇(DON)广泛存在于受污染的谷物和饲料中。体内和体外研究表明,ZEA和DON均可影响雌性动物的繁殖性能,引起生殖器官、胎儿形态,生殖细胞成熟率,性激素分泌的改变。本文综述了ZEA和DON对雌性动物繁殖性能的影响及潜在的作用机制。
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| 关 键 词： | 玉米赤霉烯酮 脱氧血腐镰刀菌烯醇 雌性动物 生殖毒性 作用机制 |
Reproductive Toxicities and Functional Mechanisms of Female Animals Induced by Deoxynivalenol and Zearalenone |
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| Abstract: | Fusarium mycotoxins, which included zearalenone and deoxynivalenol, are widespread in cereals and feedstuffs. Previous studies showed that ZEA and DON could result in reproductive disorders of female do-mestic animals in vivo and in vitro, such as the functional and morphological alterations in both reproductive or-gans and germ-cell, and the disorder of sex hormones secretion. This paper summarizes individual and com-bined reproductive toxicities of DON and ZEA in female domestic animals. Also, the related mechanisms of the two mycotoxins were discussed. |
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| Keywords: | zearalenone deoxynivalenol female animal reproductive toxicity functional mechanism |
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