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Persistence of oxytocin receptors in the bovine uterus during the first 7 d after calving: An immunohistochemical study
Authors:Cyril S. Perumamthadathil  Walter H. Johnson  Stephen J. LeBlanc  Robert A. Foster  Tracey S. Chenier
Affiliation:Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 and EH Graham Centre for Agricultural Innovation, Charles Sturt University, Wagga Wagga, NSW, Australia-2678 (Perumamthadathil, Johnson, LeBlanc, Chenier); Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 (Foster).
Abstract:Persistence of the oxytocin receptor (OTR) in the bovine uterus during the first 7 d after calving was investigated by means of immunohistochemical staining. Immunoreactive OTRs were present in different locations in the uterus on almost all days except day 2, when staining was seen only in the endothelium of blood vessels in the endometrium and myometrium. This finding supports the hypothesis that oxytocin may be ecbolic in cows through the 1st week post partum, but further studies are required to assess the receptor functionality during this period.
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