| 禽用活疫苗外源病毒污染情况的调查研究 |
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| 引用本文： | 刘丹、侯力丹,李启红,黄小洁,李俊平,杨承槐.禽用活疫苗外源病毒污染情况的调查研究[J].中国兽药杂志,2018,52(4):19-25. |
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| 作者姓名： | 刘丹、侯力丹 李启红 黄小洁 李俊平 杨承槐 |
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| 作者单位： | 中国兽医药品监察所,,,,中国兽医药品监察所 |
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| 基金项目： | 国家重点研发计划“畜禽重大疫病防控与高效安全养殖综合技术研发”重点专项（2016YFD0500800,2016YFD0500809） |
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| 摘 要： | 为对禽用活疫苗污染外源病毒的情况进行彻底摸底调查,抽取了目前使用量大、覆盖面广的禽用活疫苗重点品种共8种28批,涉及18家国内生产企业、7家国外企业,疫苗生产用SPF鸡胚来自国内8家企业。按照《中国兽药典》2010年版三部鸡检查法和《欧洲药典》对抽检的禽病活疫苗进行了外源病毒污染和禽腺病毒污染检验。结果显示所抽检的禽用活疫苗均无外源病毒污染和禽腺病毒污染,表明我国禽用活疫苗的质量控制和安全性良好。
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| 关 键 词： | 禽用活疫苗 外源病毒 腺病毒 污染 |
| 收稿时间： | 2017/5/31 0:00:00 |
| 修稿时间： | 2018/1/9 0:00:00 |
Investigation about the Extraneous Virus Contaminations of the Avian Live Vaccines |
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| Institution: | China Institute of Veterinary Drug Control,,,, |
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| Abstract: | In order to investigate the extraneous virus contaminations of the avian live vaccines, the avian live vaccines which were widely used and covered were extracted, involving 18 domestic production enterprises, 7 foreign enterprises, the SPF chicken embryo used for the vaccine production were came from eight domestic enterprises. According to chicken test of "the Veterinary Pharmacopoeia of the People''s Republic of China" (2010) and "Investigation Plan into the Group I Adenovirus Contaminations of the Avian Live Vaccines", the common extraneous viruses and group I adenovirus were tested. The results showed that the 28 batches avian live vaccines were not contaminated with extraneous viruses and group I adenovirus, indicating the quality control and safety of the avian live vaccines were good. |
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| Keywords: | Avian Live vaccines Extraneous Virus group I adenovirus Contamination |
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