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World association for the advancement of veterinary parasitology (W.A.A.V.P.) guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine and ovine)
Authors:K G Powers  Chairman
Institution:

Food and Drug Administration, Bureau of Veterinary Medicine, Building 328A, BARC-East, Beltsville, MD 20705, U.S.A.

American Cyanamid Co., P.O. Box 400, Princeton, NJ 08540, U.S.A.

Institut für Parasitologie der Universität Zürich, Winterthurerstrasse 266, CH-8057, Zurich, Switzerland

Central Veterinary Laboratory, W-Byfleet, Weybridge, KT15 3NB, Surrey, Gt. Britain

Health of Animals Directorate, Agriculture Canada, P.O. Box 1410, Sackville, N.B. EOA3CO, Canada

Abstract:During the 8th International Conference of the World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) held in Sydney, Australia, in 1977, President S. Gaafar appointed a committee to prepare international guidelines for evaluating the efficacy of anthelmintic products. The goal was to develop uniform testing standards and registration requirements to expedite the testing and approval of effective products with a minimum of labor, money, and experimental animals without sacrificing scientific validity. Achievement of such a goal would mean that data from investigators in one country could be used in registering drugs in another country.

These guidelines, which were approved by the membership at the general meeting of the 9th International Conference of the W.A.A.V.P. on July 16, 1981 in Budapest, Hungary, are only a beginning in the development of uniform international methods for testing the efficacy of anthelmintics. We now propose that they be used by the scientific community recognizing that, at this time, these guidelines have not been officially reviewed or accepted by any government regulatory authority. Investigators are encouraged to evaluate this document critically and to recommend modifications promptly to the Committee so that they may be incorporated in these guidelines before the 10th International Conference to be held in Perth, Australia in 1983.

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