Production of natural methyl anthranilate by microbial N-demethylation of N-methyl methyl anthranilate by the topsoil-isolated bacterium Bacillus megaterium |
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Authors: | Taupp Marcus Harmsen Dag Heckel Frank Schreier Peter |
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Affiliation: | Lehrstuhl für Lebensmittelchemie, Universit?t Würzburg, Am Hubland, 97074 Würzburg, Germany. |
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Abstract: | Bacillus megaterium, isolated in a screening process from topsoil, was used for N-demethylation of natural N-methyl methyl anthranilate to produce natural methyl anthranilate. Maximal productivity of 70 mg/L/day was achieved under laboratory-scale conditions without further optimization. No byproducts were observed. Thus, production of "natural" methyl anthranilate using B. megaterium is a significant improvement over comparable already existing procedures. |
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