聚醚类抗生素残留分析方法研究进展

聚醚类抗生素是从链霉菌中提取出来的离子载体类抗生素,包括莫能菌素（monensin,MON）、马杜霉素（maduramicin,MAD）、盐霉素（salinomycin,SAL）、拉沙菌素（lasalocid,LAS）等,具有较广的抗虫谱,对常见的鸡艾美耳球虫有抗虫活性,对反刍动物及猪有促生长作用。由于聚醚类抗生素的不规范使用,导致其在动物性食品中残留蓄积,引起人类健康问题,因此,要加大该类抗生素残留检测强度。聚醚类抗生素的残留分析方法主要包括分光光度法、微生物检测法、色谱法（薄层层析法、高效液相色谱、液相色谱-串联质谱法）及免疫学方法。文章总结了该类抗生素的残留分析方法,并对聚醚类抗生素残留检测技术未来的研究发展方向做出展望,以期为今后多残留检测聚醚类抗生素提供参考依据。

Research Progress on Residue Analysis Methods of Polyether Antibiotics

Polyether antibiotics,including monensin,maduramicin,salinomycin,lasalocid,and so on,are produced by saprophytic fungi.They have broad-spectrum anti-parasite and activity against pathogenic Eimeria spp.in poultry and can promote ruminant and pigs growth.But normal using may lead to residue in animal foods,causing human health problems.So we need strength the detection methods of polyether antibiotics residues.In recent years,the polyether antibiotics residues detection methods include spectrophotometry,microbiological detection,chromatography (TLC,HPLC,liquid phase chromatography-tandem mass spectrometry) and immunological methods.In this paper,we summarized the detection methods of polyether antibiotics in recent years,and we also made a forecast of polyether antibiotics detection technology to provide a reference and basis for the future residue detection.