发酵中药渣对断奶仔猪生长性能、血液生化指标、抗氧化能力及免疫功能的影响

为研究发酵中药渣作为饲料添加剂替代饲用抗生素的可行性，选取21日龄三元杂交断奶仔猪120头，随机分为对照组、中药渣组、发酵中药渣组和抗生素（硫酸黏菌素）组，每组设6个重复，每个重复5头仔猪，试验期28 d。试验第28天晨饲前，从每个重复中随机选取1头体重接近组内平均值的试验猪进行前腔静脉采血，分离血清，测定其生化指标、抗氧化指标及免疫相关指标。结果表明：发酵中药渣组仔猪的料重比（F/G）显著低于对照组和抗生素组（P<0.05）；发酵中药渣组血液总蛋白和白蛋白含量均显著高于抗生素组（P<0.05），发酵中药渣组的甘油三酯和总胆固醇含量均显著低于对照组（P<0.05）；发酵中药渣组的谷胱甘肽含量及过氧化氢酶和超氧化物歧化酶活性均显著高于对照组（P<0.05）；中药渣组和发酵中药渣组血液免疫球蛋白G（IgG）、IgA、IgM含量均显著高于对照组和抗生素组（P<0.05）。综合上述结果，发酵中药渣在调节断奶仔猪血脂浓度方面可发挥一定的作用，同时可提高断奶仔猪的生长性能、抗氧化能力和免疫力，效果优于抗生素，可作为饲料添加剂代替抗生素。

Effects of Fermented Chinese Herb Residues on Growth Performance,Serum Biochemical Parameters,Antioxidant Indexes and Immune Function of Weaned Piglets

To evaluate the possibility of subtituting in-feed antibiotics with fermented Chinese herb residues (CHR) as feed additive,120 three-way cross piglets weaned at 21 days of age were randomly assigned into 4 treatment groups with 6 replicatins with 5 piglets each replication,representing control group,CHR group,fermented CHR group and antibiotic (colistin sulfate) group.At the 28th day,1 pig was randomly selected from each replication,and the blood samples were collected from the anterior vena cava in the morning before feeding.The serum was isolated for testing the biochemical parameters,antioxidant and immunological indexes.The results showed that feed gain ratio (F/G) in fermented CHR group were significantly lower than that of the control and antibiotic groups (P < 0.05); Total protein and albumin of the fermented CHR group were significantly higher than that of the antibiotic group (P < 0.05); Triglyceride and total cholesterol of the fermented CHR group was significantly lower than that of the control group (P < 0.05); Glutathione contents,catalase and superoxide dimutase activities of fermented CHR group were significantly higher than that of the control group (P < 0.05); The contents of immunoglobulin G(IgG),IgA and IgM of CHR and fermented CHR groups were significantly higher than those of control and antibiotic groups (P < 0.05).These findings suggested that the fermented CHR could present certain roles in regulating plasma lipid concentration and improved the antioxidant capacity and immunity in weaned piglets,it could be used as the substitute for antibiotics in piglets' feed.