福建省乙肝相关性肾炎患者中医体质特征的临床研究

目的 探讨福建省乙肝相关性肾炎（HBV-GN）患者中医体质分布、中医证型分布及两者的相关性。方法 HBV-GN组收集120例福建省HBV-GN患者，同时设对照组正常健康人群120例，分析两组的体质构成差异。HBV-GN组进行主要体质类型与证型的相关性分析。结果 （1）HBV-GN组以气虚质、阳虚质、阴虚质、湿热质为主，对照组则以平和质、气虚质为主。两组体质构成存在差异（P<0.001）。（2）120例HBV-GN患者脾肾阳虚43例占35.83%；气虚血瘀33例占27.50%；肝肾阴虚21例占17.50%；肝胆湿热18例占15.0%；肝郁脾虚5例占4.17%。（3）HBV-GN组主要体质类型与证型的相关性分析，显示组间构成差异具有统计学意义（P<0.001）。结论 福建省HBV-GN患者体质以气虚质、阳虚质、阴虚质、湿热质多见，HBV-GN组辨证分型以脾肾阳虚型和气虚血瘀型多见，气虚质和阳虚质与脾肾阳虚证和气虚血瘀证呈正相关。

Clinical Study of TCM Constitution on Patients with Hepatitis B Virus Associated Glomerulone Nephritis in Fujian Province

Objective To study the distributions of TCM constitution and TCM syndrome, and the correlation of the two ones, in patients with hepatitis B virus associated glomerulone nephritis (HBV-GN) in Fujian Province. Methods The HBV-GN group includes 120 patients, the control group includes 120 health persons, and then the difference of the two groups in the constitution was analyzed. The correlation between main constitutional types and syndromes was annalyzed in the HBV-GN group. Results (1) The HBV-GN group focus on constitution of deficiency of Qi, Yang, Yin and damp-heat, and the control group focus on constitution of Yin-Yang harmony and deficiency of Qi. The constitutional distributions of the two groups have significant difference(P<0.001).(2) In the 120 cases of patients, 43 cases of syndrome of Yang deficiency of spleen-kidney account for 35.83%, 33 cases of syndrome of Qi deficiency and blood stasis account for 27.50%, 21 cases of syndrome of yin deficiency of liver-kidney of account for 17.5%, 18 cases of syndrome of dampness-heat of liver and gallbladder account for 15.0%, 5 cases of syndrome of liver-stagnation and spleen-deficiency account for 4.71%. (3) The correlation analysis between main constitutional types and syndromes in the HBV-GN group shows that differences between groups have statistical significance(P<0.001). Conclusion The TCM constitution in patients with HBV-GN in Fujian Province focus on constitution of deficiency of Qi, Yang, Yin and damp-heat. The main syndromes of the HBV-GN group focus on syndrome of Yang deficiency of spleen-kidney and syndrome of Qi deficiency and blood stasis. The constitution of deficiency of Qi, deficiency of Yang shows the positive correlation with syndrome of yang deficiency of spleen-kidney, and Qi deficiency and blood stasis.