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An improved microbiological procedure for detection of streptomycin residues in milk and animal tissues.
Authors:Henry Sø  gaard
Affiliation:Odense Municipal Laboratory, Lille Tornbjerg Vej 24, DK-5260 Odense, SØ Denmark
Abstract:A method is described which allows detection of 0.025 µg streptomycin sulfate per ml. This represents an improvement of sensitivity by 8 times when compared with the currently used method. By adding penicillin to the assay medium in subinhibitory concentrations, a synergistic effect of streptomycin and penicillin is exerted towards the test organism, Bacillus subtilis, resulting in an increased sensitivity to streptomycin.
Keywords:synergism   penicillin   streptomycin   antibiotic residues
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