| 新书推荐：《中国花卉病虫原色图鉴》 |
| |
| 摘 要： |
|
Influence of serum contained Tongmai herbal medicine on intracellular calcium concentration and L-type calcium channel in anoxic myocardial cells |
| |
| Authors: | LI Tong SUN Ming ZHOU Hong-yan LONG Kai-chao LIU Sui-xin HE Fei |
| |
| Institution: | Department of Cardiology, Xiangya Hospital, Zhongnan University, Changsha 410008, China |
| |
| Abstract: | AIM: To observe the influence of serum contained Tongmai herbal medicine on calcium overload of the anoxic myocardial cells. METHODS: Serum contained Tongmai herbal medicine was prepared with the serum pharmacological method and the model of anoxic myocardial cells was established. The intracellular free calcium concentration and the expression of the L-type calcium channel were determined with Fura-2/AM and RT-PCR, respectively. RESULTS: The serum contained Tongmai herbal medicine and levo-anlodipine decreased the intracellular free calcium concentration in the anoxic myocardial cells. The serum contained Tongmai herbal medicine also suppressed the expression of L-type calcium channel in the anoxic myocardial cells, but levo-anlodipine had no effect on the expression of L-type calcium channel. CONCLUSION: Tongmai herbal medicine can attenuate calcium overload in anoxic my-ocardial cells. |
| |
| Keywords: | ifferentiation Fetal liver Neurons Sca-1+ cells |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《园艺学报》浏览原始摘要信息 |
| 点击此处可从《园艺学报》下载免费的PDF全文 |
