| 犬瘟热病毒高压灭活疫苗的制备与应用 |
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| 引用本文： | 夏咸柱,池元开.犬瘟热病毒高压灭活疫苗的制备与应用[J].中国兽药杂志,2000,34(2):6-8. |
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| 作者姓名： | 夏咸柱 池元开 |
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| 作者单位： | [1]解放军军需大学兽医研究所 [2]吉林大学国家超硬材料重点实验室 |
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| 摘 要： | 本试验用静水压高压灭活的方法对ＣＤＶ进行灭活，并加入蜂胶佐剂制备犬瘟热病毒高压灭活疫苗。将此灭活疫苗免疫接种ＣＤＶ易感犬，同时以用福尔马林灭活的犬瘟热病毒灭活疫功为对照，检测结果表明：犬瘟热病毒高压灭活疫苗安全、可靠，其诱导试验犬所产生中和抗体的能力明显高于该病毒的福尔马林灭活苗，临床应用证明该疫苗对犬的保护率达８９％。
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| 关 键 词： | 犬瘟热病毒 灭活疫苗 制备 静水压商压灭活 免疫 |
Preparation and Application of the Pressure\|Inactivated Vaccine against Cannine Distemper Virus |
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| XIA Xian\|zhu,CHI Yuan\|bin,YU Chun,WANG Xie\|mer,HUANG Geng,WANG Yun\|hai,LIU Hai\|tao.Preparation and Application of the Pressure\|Inactivated Vaccine against Cannine Distemper Virus[J].Chinese Journal of Veterinary Drug,2000,34(2):6-8. |
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| Authors: | XIA Xian\|zhu CHI Yuan\|bin YU Chun WANG Xie\|mer HUANG Geng WANG Yun\|hai LIU Hai\|tao |
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| Abstract: | The pressure\|inactivated vaccine against canine distemper virus(CDV) was prepared by hydrostatic pressure.The results of safety,efficacy and clinic application tests showed the vaccine had better immunogenicity and could be used safely and conveniently.The ability of the pressure\|inactivated vaccine inducing CDV SN antibody was better than that of the formalininactivated vaccine,and its protection efficiency come up to 89%. |
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| Keywords: | CDV pressure\|inactivated vaccine |
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