The effect of the anesthetic Tilest in swine

The clinical signs and effects on the cardio-respiratory system of Tilest were checked out in weaners. The intramuscular injection of 10 mg/kg BW Tilest caused a rapid immobilisation on an average duration of 33.7 +/- 15 minutes. The muscle relaxation was generally good. Analgesia could not obtained. Heart- and respiratory-rates increased during lateral recumbency. Blood pressure decreased initially. The influence on the arterial blood pH-value and the blood gases are insignificant. In connection with trials to get up the lactate value and the body temperature increased. The CK- and ASAT-activities increased 2 to 6 hours after injection with a wide individual variation. During recovery the pigs were excited and salivated.