六味地黄汤及其君药对小鼠免疫调节作用的影响

为探讨六味地黄汤和地黄对小鼠免疫功能的影响，分别给小鼠灌服高、低剂量的六味地黄汤复方和地黄水提液，测定小鼠的体重、胸腺和脾重量，腹腔巨噬细胞吞噬功能及血液中白细胞和红细胞数。结果表明，试验组小鼠的体重、胸腺和脾脏重量、血液中淋巴细胞数和红细胞数增加，腹腔巨噬细胞吞噬功能增强。提示高剂量的六味地黄汤复方和地黄均可增强小鼠机体的免疫功能，且六味地黄汤复方的效果优于地黄。

Effect of Liuwei Dihuang Tang and Principal Drug on Immunomodulation in Mouse

o measure and assess the influence of Liuwei Dihuang Tang and Dihuang on immune function in mouse. The mice were drenched respectively with Liuwei Dihuang Tang and Dihuang at high and low dose, then the body weight, thymus gland weight and spleen weight, and the phagocytic index of macrophage, and the quantity of WBC and RBC were determined. The results showed that the body weight, thymus gland weight and spleen weight, the number of lymphocyte and RBC of mice in experimental groups were increased, the phagocytosis function of macrophage of mice in experimental groups were enhanced. This indicated that the immune function of mice was enhanced by Liuwei Dihuang Tang and Dihuang at high dose, and Liuwei Dihuang Tang were better than Dihuang.