丹皮酚和厚朴酚体外抗菌作用的研究

为开发高效、安全的中草药抗菌促生长剂，采用微量肉汤稀释法测定了丹皮酚和厚朴酚对13种临床常见病原菌的体外抑菌活性。结果：丹皮酚和厚朴酚对13种临床常见病原菌均有不同程度的抗菌作用，丹皮酚对嗜水气单胞杆菌的作用最好（MIC为160μg／ml），对肠道革兰氏阴性杆菌（MIC为320μg／ml）作用稍好于厚朴酚（MIC为640μg／ml）；厚朴酚对葡萄球菌（MIC为160μg／ml）抑制作用强于丹皮酚（MIC为320μg／ml）。

Study on Antibacterial Effect of Paeonol and Magnolol in vitro

Object：To discover high performance and safe antibacterial growth promotion additives from Chinese herbal medicine ,antibacterial activity of Paeonol and Magnolol to 13 strains pathogenic bacteria in vitro were tested. Method： Broth Micro - dilution Method in vitro. Resuh：Paeonol and Magnolol were observed various antibacterial activity in vitro to 13 strains pathogenic bacteria. The highest inhibiting aetion of Paeonol was tested to Aeromonas hydrophila （ MIC = 160 μg/ml）. Inhibiting action of Paeonol was stronger to Gram - Negative bacillus（ MIC = 320 μg/ml）than Magnolol（640 μg/ml）, and lower to Staphylococcus aureu （320 μg/ml） than Magnolol（ 160 μg/ml）.