草鱼出血病的组织病理研究

草鱼出血病是由呼肠孤病毒引起的一种急性传染病。病鱼全身出血，鱼的红细胞、白细胞及血红蛋白都明显地低于健康鱼。病毒侵袭草鱼后，小血管的内皮广泛受损，引起弥漫性血管内凝血，从而大量消耗了血液中的凝血因子，引起广泛性出血。由于循环血量减少和小血管阻塞，导致大多数组织和器官缺氧而变性和坏死；尤其是造血组织的坏死，更加速病鱼死亡。此外，还在草鱼血液中首次发现嗜碱粒细胞，查明了草鱼出血病同草鱼肠炎病的肠道组织病变之间的差异。

HISTUPATHULOGICAL STUDIES ON THE HEMQRRAGE DISEASE DF GRASS CARP

The hermorrage disease of grass carp (Ctenopharygodon idella) is an actue infection caused by Reovirus. The symtoms of the disease is that the whole body and all organs of the fish appears bleeding. The number of erythrocyte, leucocyte and hemoglobin of the diseased fish are obviously less than the healthy one, and that of artifically infected fish are much less than that of naturally diseased fish. The bassphils is first found in the fish blood. The small blood vessels are extensively damaged and the microthrombi are formed. The muscle, intestines, livers, spleen, kidneys and gills of the fish appear bleeding, degenerated and necrotic. There are acidophilic inclusive bodies in the cytoplasm of liver cells.