绵羊实验性黄花棘豆中毒的病理观察

用发病区的黄花棘豆草对10只绵羊进行了人工饲喂试验。饲喂这种毒草经一定时间后,全部被试动物陆续发生了和自然病例相同的临床症状,主要表现沉郁和神经功能异常。对中枢神经系统用病理方法检查揭示,脑干神经核里的神经细胞和小脑浦肯野氏细胞发生了极严重的空泡变性,淋巴结和脾的网状内皮细胞以及肝、肾实质细胞也发现同样的病变。显然,动物的神经和免疫功能受损。作者认为,病初或中毒轻微时,与生命有关的细胞成分还不会发生死亡,所以在停止饲喂毒草,并及时给予治疗后,有可能使病情好转或痊愈。

PATHOLOGIC OBSERVATION ON EXPERIMENTAL POISONING OF OXYTROPIS OCHROCEPHALA BUNGE ( LOCOWEED ) IN SHEEP

An artificial feeding experiment was conducted on 10 sheep with Oxytropis Ochrocephala Bunge collected from affected areas. After a period of time, all experimental animals appeared the same clinical signs, which mainly showed depression and neurofunctional disturbances, as natural cases. The pathological examination of the central neural system revealed that there is extreme vacuolation in the nerve cells in nerve nuclei of brain stem and in cerebellum purkinje's cells, the same pathological changes were also found in reticuloendothelial cells of lymphonodes and the spleen, Parenchymal cells of the liver and kidney. It is obvious that nerve and immunologic function of the animals were damaged. It is suggested that cells relating to life should not die at the beginning of the illness or when slight poisoning, therefore it could be possible that the cases' condition take a favourable turn or cure after stopping to feed Oxytropis Ochrocephala Bunge and timely medical treatment.