Spontaneous internal desynchronization of locomotor activity and body temperature rhythms from plasma melatonin rhythm in rats exposed to constant dim light |
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| Authors: | Jacopo Aguzzi Nicole M Bullock and Gianluca Tosini |
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| Institution: | (1) Neuroscience Institute and NSF Center for Behavioral Neuroscience, Morehouse School of Medicine, Atlanta, GA 30310-1495, USA;(2) Instituto de Ciencias del Mar (ICM-CSIC), Paseo Maritimo de la Barcelonesa 37-49, 08003 Barcelona, Spain |
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| Abstract: | Background We have recently reported that spontaneous internal desynchronization between the locomotor activity rhythm and the melatonin
rhythm may occur in rats (30% of tested animals) when they are maintained in constant dim red light (LLdim) for 60 days. Previous work has also shown that melatonin plays an important role in the modulation of the circadian rhythms
of running wheel activity (Rw) and body temperature (Tb). The aim of the present study was to investigate the effect that desynchronization of the melatonin rhythm may have on the
coupling and expression of circadian rhythms in Rw and Tb. |
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