Changes in serum C-reactive protein levels in dogs with various disorders and surgical traumas |
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| Authors: | S Yamamoto T Shida S Miyaji H Santsuka H Fujise K Mukawa E Furukawa T Nagae M Naiki |
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| Institution: | (1) Department of Immunology, Faculty of Environmental Health, Azabu University, 229 Sagamihara, Kanagawa;(2) Department of Veterinary Radiology, School of Veterinary Medicine, Azabu University, 229 Sagamihara, Kanagawa;(3) Department of Veterinary Clinical Pathology, Azabu University, 229 Sagamihara, Kanagawa;(4) Institute for Experimental Animals, Yamanashi Medical College, 409-38 Tamaho, Yamanashi;(5) Mie Research Laboratory, Sanwa Kagaku Kenkyusho Co. Ltd, Hokusei, 511-04 Inabe, Mie;(6) Department of Veterinary Science, The National Institute of Health, Shinjuku, 162 Tokyo, Japan |
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| Abstract: | The serum levels of C-reactive protein (CRP) produced as an inflammatory response in dogs with various disorders and surgical traumas were measured by enzyme-linked immunoabsorbent assay and slide reversed passive latex agglutination test (RPLA). The CRP levels were greatly increased 1–2 days after surgery in most of the dogs (n=29) subjected to surgery. These levels had markedly decreased by the time the sutures were removed. In dogs with various disorders (n=58), the serum CRP levels at first diagnosis were high in infectious diseases. In dogs from which paired serum samples were examined, the serum CRP usually showed a decrease with improvement in the condition (n=11) or a terminal increase (n=4) but, conversely, some showed an increase with improvement in the condition (n=3).Abbreviations CRP
C-reactive protein
- ELISA
enzyme-linked immunoabsorbent assay
- Latex
soap free latex
- RPLA
reversed passive latex agglutination |
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| Keywords: | acute phase proteins dogs C-reactive protein enzyme-linked immunoabsorbent assay inflammation serum surgery |
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