| 蓝舌病病毒基因产物及其生物学功能 |
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| 引用本文： | 童亮,柴俊,张以芳,肖晶.蓝舌病病毒基因产物及其生物学功能[J].中国畜牧兽医,2010,37(7):132-135. |
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| 作者姓名： | 童亮 柴俊 张以芳 肖晶 |
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| 作者单位： | (云南农业大学动物科技学院，昆明 650201） |
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| 基金项目： | 云南省高端科技人才引培项目 |
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| 摘 要： | 蓝舌病病毒(bluetongue disease virus,BTV)是呼肠孤病毒科环状病毒属的双股RNA病毒,其核酸由3个大片段(L1～L3)、3个中片段(M4～M6)和4个小片段(S7～S10)等10个节段组成,分别编码7种结构多肽(VP1～VP7)和4种非结构多肽(NS1、NS2、NS3a、NS3b)。通过dsRNA基因组进行体外翻译,再根据各基因与所编码蛋白的关系,查明了各基因编码的蛋白质及其分子质量和功能。
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| 关 键 词： | 蓝舌病病毒 基因结构 基因产物 编码蛋白 生物学功能 |
The Gene Product of the Bluetongue Virus and its Biological Function |
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| TONG Liang,CAI Jun,ZHANG Yi-fang,XIAO Jing.The Gene Product of the Bluetongue Virus and its Biological Function[J].China Animal Husbandry & Veterinary Medicine,2010,37(7):132-135. |
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| Authors: | TONG Liang CAI Jun ZHANG Yi-fang XIAO Jing |
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| Institution: | (College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China) |
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| Abstract: | Bluetongue disease virus, double-stranded RNA, a member of Orbivirus genus within Reoviridae family, consisting of 10 segments of different sizes nucleic acid (L1 to L3, M4 to M6 and S7 to S10) with seven structural proteins（VP1 to VP7）and four non-structural proteins（NS1, NS2, NS3a, NS3b）. The functions and sizes of the proteins encoded by the 10 segments nucleic acid, has been determined by the vitro translation of the genome dsRNA and expression and functional characterization. |
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| Keywords: | bluetongue disease virus genetic structure gene product encoded proteins biological function |
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