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Genotypic and phenotypic characterisation of Escherichia coli strains associated with porcine pyelonephritis
Authors:Krag Louise  Hancock Viktoria  Aalbaek Bent  Klemm Per
Institution:Department of Veterinary Pathobiology, Copenhagen University, DK-1870 Frederiksberg, Denmark.
Abstract:Urinary tract infection (UTI) is a severe problem in humans as well as in many domestic animals like pigs. The most frequent infectious agent in UTI is uropathogenic Escherichia coli. Such strains have been extensively characterised with respect to virulence and fitness factors as well as clonal type when it comes to human isolates. However, relatively little has been done to characterise the corresponding porcine strains. On this background we have analysed 20 porcine pyelonephritis E. coli strains isolated from infected pig kidneys. The strains were quite distinct from that of human uropathogenic strains with regards to adhesion profile and haemolysin production. Also, the clonal profiles differed from that of human infections since our strains all belonged to the E. coli clonal groups A and B1.
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