Cases with manifestation of chemodectoma diagnosed in dogs in Department of Internal Diseases with Horses,Dogs and Cats Clinic,Veterinary Medicine Faculty,University of Environmental and Life Sciences,Wroclaw, Poland |
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Authors: | Agnieszka Noszczyk-Nowak Marcin Nowak Urszula Paslawska Wojciech Atamaniuk Jozef Nicpon |
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Affiliation: | 1.Department of Internal Diseases with Horses, Dogs and Cats Clinic, Veterinary Medicine Faculty, University of Environmental and Life Sciences Wroclaw 50-366, Poland;2.Department of Pathological Anatomy Veterinary Medicine Faculty, University of Environmental and Life Sciences Wroclaw 50-366, Poland;3.Department and Clinic of Surgery, Veterinary Medicine Faculty, University of Environmental and Life Sciences Wroclaw 50-366, Poland |
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Abstract: | In the period of 3 years, 9 tumours of chemodectoma were supravitally diagnosed and histopathologically verified in dogs. In this period 15 351 dogs were admitted to the Clinic of Dogs and Cats and 2 145 dogs were examined in the cardiological outpatient clinic for dogs. This tumour is located in a typical place - at the base of the heart. Most frequently the tumour manifested in older boxers. Only in one case such a tumour was diagnosed in another breed of dogs. The tumours ranged in size between 3 and 16 cm in diameter. The principal sign accompanying tumours of cardiac base involved dyspnoea but in 3 cases the tumours yielded no clinical signs. All the diagnoses were additionally verified using immunohistochemical examination. We used antibodies to chromogranin A (clone DAK-A3 1:100), synaptophysin (clone SY38 1:20) and neuron-specific enolase (clone BBS/NC/VI-H14 1:150). An immunohistochemical examination is vital for the diagnosis since it allows to differentiate histologically distinct types of neoplasia which may locate in the same site and may manifest a similar histological pattern. |
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