| 牛磺胆酸抗炎作用研究 |
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| 引用本文： | 李培锋,薛原,关红.牛磺胆酸抗炎作用研究[J].内蒙古农业大学学报(自然科学版),2007,28(1):1-5. |
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| 作者姓名： | 李培锋 薛原 关红 |
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| 作者单位： | 1. 内蒙古农业大学动物科学与医学学院,呼和浩特,010018
2. 东北林业大学野生动物资源学院,哈尔滨,150000 |
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| 摘 要： | 目的:研究牛磺胆酸的抗炎作用。方法:采用多种动物模型,观察牛磺胆酸对炎症的影响。结果:牛磺胆酸能够降低炎症组织毛细血管的通透性,抑制炎症性肿胀,抑制NO、PGE2、组胺等炎症介质的产生。结论:牛磺胆酸具有明显的抗炎效应,其抗炎作用主要是通过抑制炎症介质的产生而实现的。
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| 关 键 词： | 牛磺胆酸 抗炎作用 组胺 |
| 文章编号： | 1009-3575（2007）01-0001-05 |
| 修稿时间： | 2006-10-26 |
STUDIES ON ANTI-INFLAMMATORY EFFECT OF TAUROCHOLIC ACID |
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| LI PEI-feng,XUE-yuan,GUAN-hong.STUDIES ON ANTI-INFLAMMATORY EFFECT OF TAUROCHOLIC ACID[J].Journal of Inner Mongolia Agricultural University(Natural Science Edition),2007,28(1):1-5. |
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| Authors: | LI PEI-feng XUE-yuan GUAN-hong |
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| Institution: | 1. College of Animal Science and Medicine, Inner Mongolia Agricultural University, Huhhot 010018, China; 2. College of wildlife resource of Northeast Forest University,Haier bin 150000,China |
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| Abstract: | The anti-inflammatory effects of Taurocholic Acid on acute and chronic inflammation were studied with several kinds of animal models.The experimental results showed that Taurocholic Acid can reduce the capillary permeability in inflammation tissue,can restrain the inflamed swelling and inhibit the generation of inflammatory mediators,such as NO,PGE2 and histamine.Therefore,the Taurocholic Acid can significantly inhibit the inflammation by reducing the generation of inflammation mediators. |
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| Keywords: | NO PGE2 |
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