Immunisation of pregnant sows with a live Salmonella cholerae suis vaccine |
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Authors: | J Hanna WA Ellis JJ OBrien |
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Institution: | Veterinary Research Laboratories, Stormont, Belfast BT4 3SD Northern Ireland |
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Abstract: | Sows were immunised subcutaneously with a live Salmonella cholerae suis (SCS) vaccine prior to farrowing. Serological tests demonstrated a high level of SCS colostral antibodies at parturition. Piglet sera negative for antibodies at birth contained a high level of SCS antibodies 24 h after the ingestion of vaccinated sow colostrum. Experiments were carried out to establish if these maternally derived antibodies could protect the piglets against an intranasal (IN) challenge with a field isolate of SCS. It was concluded that pregnant sows could be safely immunised with a live SCS vaccine thus providing their piglets with a passive immunity which protected them against an intranasal challenge. |
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