猪流感病毒的基因组结构及跨种属传播

猪是禽和哺乳动物流感病毒的中间宿主和产生重组病毒的混合器,猪流感病毒基因重排现象非常普遍。从猪流感病毒的形态结构、抗原性、基因组与主要编码蛋白、基因重排与跨种属传播等方面,对其研究情况进行了综述,以期为进一步了解猪流感病毒基因重排及种间传播机制,更好的防控流感疫情提供参考。

The genome structure and interspecies transmission of Swine influenza virus

Abstract: Pigs are susceptible to both avian and mammalian influenza viruses and have been proposed to be intermediate hosts, and mixing vessels for the generation of pandemic influenza viruses through reassortment or adaptation to the mammalian host. The genetic recombination of Swine influenza viruses is very common. In this review, we describe the morphological structure, antigenicity, genome structure and important proteins of swine influenza viruses, also the genetic recombination and interspecies transmission, we summarize the research process of swine influenza viruses. The present study provides evidence for the research of the genetic recombination and interspecies transmission of Swine influenza viruses, will help to the prevention and control of influenza outbreaks.