Abstract: | Colostrum and milk samples were obtained from five Yorkshire gilts through manual expression of glands at the onset of parturition; at 1, 2, 4 and 8 h after birth of the first piglet and at 8-h intervals thereafter until 96 h. Oxytocin (30 units) was used to stimulate milk ejection for all samples except during parturition. Samples were frozen until subjected to a validated radioimmunoassay for estrone (E1). In a preliminary study no differences existed in concentrations of E1 among various glands. Therefore, mean of values obtained from three randomly selected glands was used for analysis in the main trial. Concentration of E1 at birth averaged 13.6 +/- 1.78 ng/ml (X +/- SE), and decreased to 6.05 +/- .80, 3.12 +/- .60, 1.42 +/- .30, .69 +/- .20 and .33 +/- .92 ng/ml at 4, 8, 16, 32 and 96 h, respectively. The postpartum decrease in the concentration of E1 in the milk is most likely due to the loss of the placental source. |