Variation among pathologists in histologic grading of canine cutaneous mast cell tumors. |
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| Authors: | Nicole C Northrup Barry G Harmon Tracy L Gieger Cathy A Brown K Paige Carmichael Anapatricia Garcia Kenneth S Latimer John S Munday Pauline M Rakich Lauren J Richey Nancy L Stedman An-Lin Cheng Elizabeth W Howerth |
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| Institution: | Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA. |
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| Abstract: | Ten veterinary pathologists at 1 veterinary institution independently assigned histologic grades to the same 60 canine cutaneous mast cell tumors (MCTs). There was significant variation among pathologists in grading the MCTs (P < 0.001). The probability of assigning a low grade was significantly higher for the pathologists in this study who use a published reference for histologic grading of canine cutaneous MCTs that allows subcutaneous MCTs or MCTs with mitotic figures to be included in the low-grade category (P < 0.0001 and P < 0.0001, respectively). |
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