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Progress in depression based on metabolomics
Authors:LIU Zhen  ZHOU Ning  LIU Tong  WANG Yang-yang  LIU Zhen-hui  ZHANG Ya-wen  ZHENG Xiao-ke  FENG Wei-sheng
Affiliation:1.Henan University of Chinese Medicine;2.The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China
Abstract:Depression is a kind of common mental disorder, which seriously endangers people's health and life. Its pathogenesis is complex and still not completely clear. Metabolomics is an emerging method of systematic biology research that is systematic and holistic. These characteristics are consistent with the complexity of depression. Therefore, more and more studies have been carried out on depression based on metabolomics, which provide us with a wealth of data and information. This paper reviewed researches of depression based on metabolomics, and summarized biomarkers and metabolic pathways related to depression patients and depression model animals, in order to provide more information and direction for the study of depression.
Keywords:Depression  Pathogenesis  Metabolomics  Biomarkers  Metabolic pathway  
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