Drinking rate in juvenile Atlantic salmon,Salmo salar L fry in response to a nitric oxide donor,sodium nitroprusside and an inhibitor of angiotensin converting enzyme,enalapril |
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Authors: | Juan Fuentes J. C. McGeer F. B. Eddy |
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Affiliation: | (1) Department of Physiology, Faculty of Biological Sciences, University of Santiago, 15706 Santiago de Compostela, Galicia, Spain;(2) Department of Biological Sciences, University of Dundee, DD1 4HN Dundee, Scotland, UK |
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Abstract: | Drinking in freshwater juvenile salmon was investigated in response to vasodilation by sodium nitroprusside (SNP), a nitric oxide donor, which significantly increased blood vessel diameter in Atlantic salmon alevins. Atlantic salmon fry (1–3 g), as previously shown, drank at a significant rate in fresh water which doubled to about 1.2 ml kg–1 h–1 following injection of SNP (100 mol kg–1), through dilation of body vasculature and activation of a vasoconstrictive mechanism, the endogenous renin angiotensin system (RAS). This response was 50% inhibited by injection of about 100 mg kg–1 enalapril. Fry increased drinking in response to SNP administered in the water, though the concentration required for maximal response, 1.6 mmol l–1, was much greater than for injected SNP; this response was also inhibited by enalapril injection. Possible involvement of the gill vasculature and branchial osmoreceptors or baroreceptors in control of the drinking response is discussed. |
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Keywords: | salmon fry drinking nitric oxide renin angiotensin system |
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