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Synthesis and insecticidal activity of lipophilic amides. Part 5: Influence on activity of varying the substituent on nitrogen
Authors:Michael Elliott  Andrew W. Farnham  Norman F. Janes  Diana M. Johnson  David A. Pulman
Abstract:Isomerisation or shortening of the 2-methylpropyl group in (2-methylpropyl)-6-phenylhexa-2, 4-dienamide lowers insecticidal activity, as does methylation at nitrogen. Methylation at each carbon atom in turn, and, within limits, in combination, gives compounds with substantial, sometimes increased, activity. Cyclic and olefinic equivalents of the effective alkyl substituents are mostly less active.
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