山东规模化养殖场毛皮动物多重感染病原学分析

2012—2013年间,山东10个地市多家毛皮动物养殖场养殖的毛皮动物（狐狸、貉子、水貂）出现腹泻,皮肤湿疹,神经症状,空怀、流产、出血性肺炎等症状和病变类似的疫情,为探明其病因,本研究对发病规模化毛皮动物养殖场发病情况进行调查,并对送检的病料进行病原学检查,结果发现,犬瘟热病毒、细小病毒、阿留申病毒感染率分别为54.21%、47.30%、31.35%;肺炎克雷伯菌、奇异变形杆菌、肺炎双球菌、大肠杆菌、沙门杆菌、绿脓杆菌、加德纳菌的感染率分别为37.58%、25.05%、21.81%、14.04%、12.53%、10.37%、8.21%;犬瘟热病毒、细小病毒、阿留申病毒、肺炎克雷伯菌、奇异变形杆菌、肺炎双球菌6种病原的单独感染、二重感染、三重感染、四重感染分别为22.03%、39.52%、36.07%、2.38%,未见五重以上的感染。结果表明,近两年造成山东规模化场毛皮动物发病主要原因是由犬瘟热病毒、细小病毒、阿留申病毒与肺炎克雷伯菌、奇异变形杆菌、肺炎双球菌多重感染所致,这为规模化毛皮动物养殖场有效地控制疫病提供了理论依据。

The etiology analysis of multiple infections in Shandong scale fur farms

In 2012--2013, some animals of fur animal breeding farms in 10 different areas of Shandong appear diarrhea, skin rash, neurological symptoms, empty cup, miscarriage and hemorrhagic pneumonia similar and symptoms. In order to investigate its causes, the morbidity investigation of the large-scale onset fur animal farms were carried out . The results showed that the infection rates of Canine distemper virus, Parvovirus, Aleutian viruses were 54.21%, 47.30 %, 31.35 %, the infection rates of Klebsiella pneumoniae , Proteus mirabilis , Streptococcus pneumoniae , Escherichia coli , Salmonella, Pseudomonas aeruginosa , Gardnerella coli were 37. 58%, 25. 05%, 21.81%, 14.04 %, 12.53 %, 10.37 %, 8.21%. The Canine distemper virus, Parvovirus, Aleutian viruses, Klebsiella pneumonia, Proteus mirabilis , Streptococcus pneumoniae , 6 kinds of pathogenic infections of single,double,triple and four infection were 22.03%, 39.52%, 36.07%, 2.38% and no more than five infection. The results indicate that the main reason for the disease was caused by the Canine distemper virus, Parvovirus,Aleutian viruses and Klebsiella pneumoniae,Proteus mirabilis, Streptococcus pneumoniae, Salmonella, Escherichia coli or mixed infection of infection. It provides a basis for the effective and targeted control of large-scale epidemics in the infectious disseases of fur animal farms.