ENTERITIS IN FOALS INDUCED BY ROTAVIRUS AND ENTEROTOXIGENIC ESCHERICHIA COLI |
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Authors: | S TZIPORI T MAKIN M SMITH F KRAUTIL |
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Institution: | Attwood Veterinary Research Laboratory, Department of Agriculture, Mickleham Road, Westmeadows, Victoria, 3047 |
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Abstract: | Colostrum-deprived, colostrum-fed or suckling foals were orally inoculated with foal rotavirus and enterotoxigenic Escherichia coli derived from a calf. Neither agent given alone caused diarrhoea in foals aged 1 or 2 days, although with rotavirus, 2 of the 3 inoculated foals became depressed 3 days after inoculation and all 3 were excreting rotavirus in the faeces. Inoculation of both agents induced diarrhoea in colostrum-deprived, colostrum-fed or suckling foals aged up to 16 days. There was an apparent age-related resistance to diarrhoea which developed between 2 and 3 weeks of age. It was related to failure of rotavirus to establish apparent infection in older foals and was independent of preinoculation maternal antibody. |
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