| Ghrelin在绵羊黄体形成过程中的表达 |
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| 引用本文： | 杜晨光,赵林旺,张小宇,郭凤英,李国俊,郭志凯.Ghrelin在绵羊黄体形成过程中的表达[J].内蒙古农业大学学报(自然科学版),2012,33(1):16-19. |
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| 作者姓名： | 杜晨光 赵林旺 张小宇 郭凤英 李国俊 郭志凯 |
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| 作者单位： | 1. 内蒙古农业大学职业技术学院,包头,014109
2. 内蒙古四子王旗脑木更苏木兽医站,四子王旗,011800 |
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| 基金项目： | 国家自然科学基金，内蒙人才基金，内蒙古自然科学基金，内蒙古高等学校科学研究项目 |
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| 摘 要： | 黄体作为卵巢上主要功能单位之一,对维持哺乳动物正常生殖的作用至关重要,而Ghrelin在调节能量平衡等多种生物学功能的积极作用,促使我们探讨Ghrelin在绵羊有腔和成熟卵泡内壁层颗粒细胞形成黄体后的表达情况,结果表明发情期黄体细胞的免疫活性远强于其前身壁颗粒细胞,而且Ghrelin mRNA相对表达量也显著高于其前身壁颗粒细胞.Ghrelin免疫活性和mRNA水平的黄体形成前后的显著变化间接的表明这一新型分子对于黄体功能变化具有潜在调控作用.
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| 关 键 词： | ghrelin 绵羊 卵泡 壁颗粒细胞 黄体 |
EXPRESSION OF GHRELIN DURING THE DEVELOPMENT OF CORPORA IUTEA IN SHEEP |
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| DU Chen-guang,ZHAO Lin-wang,ZHANG Xiao-yu,LI Guo-jun,GUO Zhi-kai.EXPRESSION OF GHRELIN DURING THE DEVELOPMENT OF CORPORA IUTEA IN SHEEP[J].Journal of Inner Mongolia Agricultural University(Natural Science Edition),2012,33(1):16-19. |
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| Authors: | DU Chen-guang ZHAO Lin-wang ZHANG Xiao-yu LI Guo-jun GUO Zhi-kai |
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| Institution: | 1(Vocational and Technical College,Inner Mongolia Agricultural University,Baotou 014109;Siziwangqi naomugensumu Veterinary Station of Inner Mongolia Siziwangqi 011800,China) |
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| Abstract: | Corpora lutea(CL) as a functional unit in the ovary is very important to the reproduction.In addition,the estrous cycle has a tight relationship with energy.It is unknown what is the role of ghrelin during the development of CL.Thus,we investigate the change of ghrelin in theca cells of antral and matured follicles and CL.The results showed that ghrelin immunoreactivity was stonger experssion in CL and fainter in theca cells of antral and matured follicles,as well as the ghrelin mRNA.Changes in the profile of immunoreactivity and ghrelin mRNA during the development of CL in estrous cycle is highly suggestive of a potential regulatory role of this novel molecule in reproductive function. |
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| Keywords: | Ghrelin sheep follicle theca cell corpora lutea |
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