首页 | 本学科首页   官方微博 | 高级检索  
     


Failure of a Subunit Bovine Herpesvirus 1 Vaccine to Protect Against Experimental Respiratory Disease in Calves
Authors:C. le Q. Darcel and K.W.F. Jericho
Abstract:In two experiments in which 31 calves were used, a bovine herpesvirus 1 subunit vaccine previously shown to elicit a strong immunological response in adult cattle failed to do so in younger animals and failed to protect against pneumonia caused by sequential exposure to virulent bovine herpesvirus 1 and Pasteurella haemolytica aerosols. One of the experimental groups had been previously inoculated with a live commercial vaccine but even this failed to elicit a strong immunological response. These results indicate that the calves were in a refractory state when immunized and may explain why similar vaccine failures occur in the field.
Keywords:
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号