Inhibition of enzymatic synthesis of pantothenate by 2,3-dichloroisobutyrate |
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Authors: | HILTON J L |
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Abstract: | The investigations reported here have shown that 2,3-dichloroisobuty-rate is uncompetitive with beta-alanine and competitive with pantoate for a site on the enzyme of pantothenate synthesis. The enzyme dissociation constant of the inhibitor was comparable to that of the competitive substrate. |
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