Therapeutic effects of beta-thujaplicin eardrops on canine Malassezia-related otitis externa |
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Authors: | Nakano Yasuyuki Matsuo Saburo Tani Hiroyuki Sasai Kazumi Baba Eiichiroh |
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Institution: | Department of Veterinary Clinical Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan. |
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Abstract: | An eardrop solution of beta-thujaplicin was examined for therapeutic effects on canine Malassezia-related otitis externa. Half to one ml of beta-thujaplicin solution of 100 microg/ml including DMSO 2% was injected everyday into both external ear canals of 31 cases for test-of-cure agreement. Fifteen score phases were established from the symptoms and cerumen smear biopsy findings, and score changes were recorded at least once a week. The means of the second and the third inspection day scores decreased significantly more than the previous value of each. In addition, the numbers of yeast-like organisms clearly decreased. These results suggest that beta-thujaplicin eardrops are effective for Malassezia-related otitis externa in dogs. |
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